Polynucleotides

Understanding comes before treatment. Read what this treatment involves, its limitations, and begin with a free consultation.

Begin your free consultation

Suitability comes first.

Suitability comes first.

Suitability comes first.

No treatment is confirmed on this page. Medical history, expectations and risk tolerance all shape whether this pathway is appropriate for you.

At a glance

What it may, and may not, do.

What it may, and may not, do.

What it is

Regenerative injectable treatment used to support skin quality in selected areas, including delicate skin where volume is not the goal.

For those who want to know more

The fuller picture.

The fuller picture.

The fuller picture.

Regenerative injectable treatment used to support skin quality in selected areas, including delicate skin where volume is not the goal.

At a glance

Appointment: Often 30 to 45 min. Plan: Usually discussed as a course. Downtime: Papules, swelling or bruising. Results: Progressive over several weeks.

Indicative guide only. Exact timing, course, recovery and suitability are confirmed after assessment.

How it works

The mechanism, without the marketing

Polynucleotides are injectable preparations made from purified DNA fragments. They are used with the aim of supporting repair, hydration, elasticity and overall skin quality. Unlike dermal filler, they are not intended to enlarge lips, project a chin or rebuild facial structure. Their role is quieter: supporting the condition of the skin itself, including selected delicate areas where volume is not the goal.

What we assess

The details that change the plan

  • Skin thickness, crepiness, hydration and elasticity

  • The exact under eye concern, skin quality, hollowing, pigmentation, oedema or vascular shadow

  • Allergy history, inflammation, infection and previous injectable treatment

  • Whether expectations match a gradual regenerative treatment

Before, during & after

What the appointment may involve

Before, assessment: The area is assessed to establish whether the visible concern comes from the skin itself or from deeper anatomy that this treatment cannot change.

During, treatment: Multiple small injections are placed in the treatment area. Temporary visible papules are common immediately afterwards.

After, recovery: Swelling, bruising, tenderness and small raised areas can occur. Delicate areas, particularly around the eyes, may remain puffy for longer in some people.

Results, course & recovery

What changes, and when

Changes are gradual and variable. A course is often discussed because the aim is cumulative skin support rather than an instant structural change. Photography and a planned review are more useful than judging the treatment day by day.

Limits, risks & alternatives

The part that should never be hidden

Polynucleotides cannot replace lost volume, lift significant laxity, erase pigment or guarantee an improvement in dark circles. Evidence and product characteristics vary, so brand, origin and intended use matter. As with any injectable, infection, prolonged swelling, inflammatory reactions and vascular complications are possible, even if uncommon.

Concerns this may relate to

Start from the why. These pages explain the concern, not just the procedure: Fine lines & wrinkles, Loss of firmness, Under eye concerns, Facial volume loss, Dry & dehydrated skin.

Begin with a free consultation

Information can narrow the possibilities. Your free consultation is where we identify the right pathway. Start your free consultation.

Still wondering?

Three common questions.

Three common questions.

Three common questions.

Can I book this treatment immediately?

Treatment can only proceed after suitability, risks, alternatives and consent have been discussed. Your consultation is free and does not obligate you to proceed.

Will I need a course?

That depends on the indication and your response. We will explain what is essential, what is optional and when it is reasonable to review before committing further.

Are results guaranteed?

No medical aesthetic treatment can guarantee a specific outcome. We discuss likely benefit, uncertainty, downtime and risk before a decision is made.

Bring the concern.
We will help find the path.

Bring the concern.
We will help find the path.

Bring the concern.
We will help find the path.

Begin your free consultation

Glow Works
Skin Clinic

Glow

Works.

Medical Doctor led skin, aesthetic, hair and body care. We begin with a free consultation, not a treatment menu.

Visit

118 Baker Street, Marylebone, London, W1U 6TU

Mon to Sat, 9am to 7pm

© 2026 Glow Works Ltd

Medical information is general; suitability is assessed individually.

It's the little things.

Glow Works
Skin Clinic

Glow

Works.

Medical Doctor led skin, aesthetic, hair and body care. We begin with a free consultation, not a treatment menu.

Visit

118 Baker Street, Marylebone, London, W1U 6TU

Mon to Sat, 9am to 7pm

© 2026 Glow Works Ltd

Medical information is general; suitability is assessed individually.

It’s the little things.

Glow Works
Skin Clinic

Glow

Works.

Medical Doctor led skin, aesthetic, hair and body care. We begin with a free consultation, not a treatment menu.

Visit

118 Baker Street, Marylebone, London, W1U 6TU

Mon to Sat, 9am to 7pm

© 2026 Glow Works Ltd

Medical information is general; suitability is assessed individually.

It's the little things.