Polynucleotides are often considered when your skin is starting to look tired, thin, crepey, dull or less resilient, but you do not necessarily want to add volume or change the shape of your face. They are part of a newer category of injectable skin treatments focused on improving skin quality rather than altering facial features.

You may come across polynucleotides described as a regenerative skin treatment, polynucleotide skin booster, salmon sperm facial or injectable skin rejuvenation treatment. In simple terms, they are used to support healthier-looking skin, particularly where the skin feels fragile, dehydrated or slow to recover.

Polynucleotides are injectable treatments made from purified DNA fragments. They are designed to support the skin’s repair processes and are commonly used in aesthetic medicine to improve skin quality, hydration, elasticity and texture.

Unlike dermal fillers, polynucleotides are not used to create volume, contour or structure. They are not designed to make lips larger, lift the cheeks or reshape the jawline. Instead, they are used more subtly, with the aim of improving the condition of the skin itself.

You may consider polynucleotide treatment if you are concerned about:

Fine lines linked to thin or crepey skin
Under-eye skin quality
Dull or tired-looking skin
Reduced firmness or elasticity
Skin that looks dehydrated or fragile
Early signs of skin ageing
Poor skin recovery or general skin resilience

Polynucleotides are commonly discussed for delicate areas such as the under-eyes, as well as the face, neck and areas where the skin quality has started to change. The under-eye area is one of the reasons many people search for under-eye polynucleotides in London, particularly when they feel the skin looks thin, tired or crepey rather than simply hollow.